IKKβ-IN-1 - CAS 2410423-31-1

IKKβ-IN-1 is a potent, orally active inhibitor of IkappaB (IKK-β) with an IC50 of 0.20 μM. It reduces the inhibition of PGE2 and TNF-α production in murine macrophages and protects mice from infection shock-induced death.

Others, IκB/IKK

NF-κB, Others

2410391

C31H30N4O4S

554.66

O=C\1N(C(=O)S/C1=C\C2=CC=C(OC3=CC=C(C#N)C=C3)C=C2)C4=CC=C(OCCCN5CCN(C)CC5)C=C4

-20°C

Ice Packs

Small Compound