IKKγ NBD Inhibitory Peptide - CAS 372146-18-4

A cell-permeable synthetic peptide NEMO-binding domain peptide (NBD peptide) corresponding to the NEMO amino-terminal alpha-helical region is shown to block TNF-alpha-induced NF-kB activation. The interaction of IKγNEMO with the IKK complex is vital for the activation of the IKK complex and the subsequent activation of NF-kB.

NF-κB

NF-κB

372124

C170H259N49O42S1

3693.3

-20°C

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Peptide