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IKP-104 - CAS 114231-14-0
IKP-104 - CAS 114231-14-0
SKU:MF-0119291-01
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Product Details
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Bioactivity
IKP-104 is a microtubule/tubulin inhibitor (IC50 = 1.31 μM) that halts cells in mitosis and the M phase by inhibiting microtubule assembly and inducing cytoskeleton microtubule depolymerization. It suppresses the growth of both murine and human tumor cell lines, exhibiting antitumor effects in mouse ascites tumor and lung cancer models. IKP-104 is applicable in research on cancers such as leukemia, lung cancer, and melanoma.
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Target
Microtubule Associated
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Related Pathways
Cytoskeletal Signaling
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CAS Number
114217
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Molecular Formula
C26H21ClFNO3
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Molecular Weight
449.9
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SMILES
O=C1C=C(C=2C=CC=CC2)N(C=3C=C(OC)C=C(OC)C3Cl)C(C=4C=CC(F)=CC4)=C1C
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Storage Temperature
-20°C
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Shipping Conditions
Ice Packs
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Category
Small Compound