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IKZF2-degrader 1 - CAS 2983840-43-1

IKZF2-degrader 1 - CAS 2983840-43-1

MF-0115320-01

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Product Details

  • Bioactivity

    IKZF2-degrader 1 (Compound 31) is a molecular glue-type degrader of IKZF2 with a DC50 of 0.5 nM. It exhibits relatively low degradation activity against CK1α, with a DC50 of 210 nM. This compound is applicable in research focused on IKZF2-dependent cancers.

  • Target

    IKZF, Molecular Glues

  • Related Pathways

    Immunology/Inflammation, PROTAC

  • CAS Number

    2983796

  • Molecular Formula

    C27H30FN7O3

  • Molecular Weight

    519.57

  • SMILES

    O=C1NC(=O)C(N2C(=O)C3=CC=C(C4=NC=5C(=NNC5C(=C4)CN6CCCC6)NC(C)C)C(F)=C3C2)CC1

  • Storage Temperature

    -20°C

  • Shipping Conditions

    Ice Packs

  • Category

    PROTAC