Ilaprazole sodium - CAS 172152-50-0

Ilaprazole sodium (IY-81149 sodium), a substituted benzimidazole prodrug, is a selective and irreversible proton pump inhibitor. A weak base, Ilaprazole accumulates in the acidic environment of the secretory canaliculus of the gastric parietal cell where it is converted to an active sulfenamide form that binds to cysteine sulfhydryl groups on the luminal aspect of the proton pump hydrogen-potassium adenosine triphosphatase (H+/K+ ATPase), thereby inhibiting the pump's activity and the parietal cell secretion of H+ ions into the gastric lumen, the final step in gastric acid production.

Proton pump, TOPK

MAPK, Membrane transporter/Ion channel

172102

0.9955

C19H17N4NaO2S

388.42

O=S(CC1=NC=CC(OC)=C1C)C2=NC3=C([N-]2)C=C(N4C=CC=C4)C=C3.[Na+]

-20°C

Ice Packs

Small Compound