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Imatinib Mesylate - CAS 220127-57-1

Imatinib Mesylate - CAS 220127-57-1

SKU:MF-0033549-01

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  • Bioactivity

    Imatinib Mesylate (STI-571) is a tyrosine kinase receptor inhibitor with antineoplastic activity (IC50s: 0.6 μM, 0.1 μM and 0.1 μM for v-Abl, c-Kit and PDGFR, respectively) .

  • Target

    C-Kit, PDGFR, Autophagy, Bcr-Abl

  • Related Pathways

    Cytoskeletal Signaling, Autophagy, Tyrosine Kinase/Adaptors, Angiogenesis

  • CAS Number

    220069

  • Purity

    >99.99%

  • Molecular Formula

    C29H31N7O·CH4SO3

  • Molecular Weight

    589.71

  • SMILES

    CS(O)(=O)=O.CN1CCN(Cc2ccc(cc2)C(=O)Nc2ccc(C)c(Nc3nccc(n3)-c3cccnc3)c2)CC1

  • Storage Temperature

    -20°C

  • Shipping Conditions

    Ice Packs

  • Category

    Small Compound