Molfinity
IMG-2005 - CAS 1229954-79-3
IMG-2005 - CAS 1229954-79-3
SKU:MF-0126580-01
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Product Details
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Bioactivity
IMG-2005 acts as an inhibitor of the TLR signaling pathway by mimicking the Toll/interleukin-1 receptor (TIR) domain of MyD88. This action prevents the homodimerization of MyD88, mitigating damage to tracheal epithelial cells and averting the onset of pulmonary immune diseases.
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Target
TLR
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Related Pathways
Immunology/Inflammation
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CAS Number
1229954-79-3
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Molecular Formula
C140H227N45O33S
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Molecular Weight
3100.65
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SMILES
C([C@@H](C(N[C@@H](CC1=CC=CC=C1)C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@@H](CC=2C=3C(NC2)=CC=CC3)C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(=O)N4[C@H](C(NCC(N[C@@H]([C@@H](C)O)C(O)=O)=O)=O)CCC4)CC(C)C)=O)C(C)C)=O)CC(O)=O)=O)CCCNC(=N)N)=O)CCCCN)=O)CCCCN)=O)=O)CCCCN)=O)CCSC)=O)CCCNC(=N)N)=O)CCCNC(=N)N)=O)CC(N)=O)=O)CCC(N)=O)=O)=O)NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@H](CC(O)=O)N)=O)CCCNC(=N)N)=O)CCC(N)=O)=O)[C@H](CC)C)=O)CCCCN)=O)[C@H](CC)C)=O)C=5C=6C(NC5)=CC=CC6
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Storage Temperature
-20°C
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Shipping Conditions
Ice Packs
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Category
Peptide