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Imlunestrant tosylate - CAS 2408840-41-3
Imlunestrant tosylate - CAS 2408840-41-3
SKU:MF-0154730-01
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Product Details
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Bioactivity
Imlunestrant tosylate (LY-3484356) is a potent, orally active selective estrogen receptor degrader (SERD) with purely antagonistic properties, effectively inhibiting estrogen receptor (ER) -dependent gene transcription and cell growth. This compound is applicable in research on ER-positive (ER+) advanced breast cancer (aBC) and endometrial endometrioid cancer (EEC) [1] [2].
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Target
Others, Estrogen Receptor/ERR
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Related Pathways
Others, Endocrinology/Hormones
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CAS Number
2408796
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Molecular Formula
C36H32F4N2O6S
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Molecular Weight
696.71
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SMILES
S(=O)(=O)(O)C1=CC=C(C)C=C1.OC1=CC=2C(=C3C(C=4C(O[C@@H]3C5=CC=C(OCCN6CC(CF)C6)C=C5)=CC(C(F)(F)F)=CC4)=CN2)C=C1
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Storage Temperature
-20°C
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Shipping Conditions
Ice Packs
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Category
Small Compound