Immuno modulator-1 - CAS 2757469-20-6

Immuno modulator-1 (compound 22) effectively suppresses the secretion of TNFα and IL-2 in human peripheral blood mononuclear cells (hPBMC), with IC50 values of 4.7 nM and 26 nM, respectively, and exhibits a 20% inhibitory effect on the hERG potassium channel at a concentration of 3 μM [1].

Potassium Channel, Others, Interleukin, TNF

Membrane transporter/Ion channel, Others, Immunology/Inflammation, Apoptosis

2757443

C32H31FN6O4

582.62

O(CC1=CC=C([C@@H](C)N2CCN(CC2)C3=C(F)C=C(C#N)C=N3)C=C1)C4=C5C(C(=O)N(C5)[C@@H]6C(=O)NC(=O)CC6)=CC=C4

-20°C

Ice Packs

Small Compound