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Immunoproteasome activator 1 - CAS 901728-48-1
Immunoproteasome activator 1 - CAS 901728-48-1
SKU:MF-0142727-01
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Product Details
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Bioactivity
Immunoproteasome Activator 1 (compound A) is a selective immunoproteasome activator that enhances the presentation of individual MHC-I binding peptides by over 100 times. It binds to the proteasomal structural subunit PSMA1 and facilitates the association of the proteasome activators PA28α/β (PSME1/PSME2) with the immunoproteasome.
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Target
Proteasome
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Related Pathways
Proteases/Proteasome, Ubiquitination
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CAS Number
901679
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Molecular Formula
C24H23N3O3
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Molecular Weight
401.46
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SMILES
O=C(NC1=CC=CC(=C1)C(=O)C)C2=CC=3C=C4C5=C(C3OC2=N)CCCN5CCC4
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Storage Temperature
-20°C
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Shipping Conditions
Ice Packs
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Category
Small Compound