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Molfinity

IN-1130 - CAS 868612-83-3

IN-1130 - CAS 868612-83-3

SKU:MF-0015012-01

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  • Bioactivity

    IN-1130 is a selective inhibitor of ALK5 with IC50 values of 5.3 nM, 36 nM, and 4.3 μM for phosphorylation of ALK5-mediated Smad3, ALK5 phosphorylation of casein and p38α mitogen-activated protein kinase.

  • Target

    ALK, TGF-beta/Smad

  • Related Pathways

    Tyrosine Kinase/Adaptors, Stem Cells, Angiogenesis

  • CAS Number

    868526

  • Purity

    0.9979

  • Molecular Formula

    C25H20N6O

  • Molecular Weight

    420.47

  • SMILES

    Cc1cccc(n1)-c1nc(Cc2cccc(c2)C(N)=O)[nH]c1-c1ccc2nccnc2c1

  • Storage Temperature

    -20°C

  • Shipping Conditions

    Ice Packs

  • Category

    Small Compound