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IN-1130 - CAS 868612-83-3
IN-1130 - CAS 868612-83-3
SKU:MF-0015012-01
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$45.88 USD
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$45.88 USD
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Product Details
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Bioactivity
IN-1130 is a selective inhibitor of ALK5 with IC50 values of 5.3 nM, 36 nM, and 4.3 μM for phosphorylation of ALK5-mediated Smad3, ALK5 phosphorylation of casein and p38α mitogen-activated protein kinase.
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Target
ALK, TGF-beta/Smad
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Related Pathways
Tyrosine Kinase/Adaptors, Stem Cells, Angiogenesis
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CAS Number
868526
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Purity
0.9979
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Molecular Formula
C25H20N6O
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Molecular Weight
420.47
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SMILES
Cc1cccc(n1)-c1nc(Cc2cccc(c2)C(N)=O)[nH]c1-c1ccc2nccnc2c1
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Storage Temperature
-20°C
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Shipping Conditions
Ice Packs
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Category
Small Compound