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INCB159020 - CAS 2923669-20-7
INCB159020 - CAS 2923669-20-7
SKU:MF-0112815-01
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Product Details
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Bioactivity
INCB159020 is an orally active inhibitor of KRAS G12D, exhibiting a KRAS G12D SPR value of 2.2 nM. It demonstrates anti-tumor activity.
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Target
Ras
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Related Pathways
MAPK, GPCR/G Protein
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CAS Number
2923642
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Molecular Formula
C37H35ClFN7O2
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Molecular Weight
664.171
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SMILES
[C@@H](C)(C=1N(C2=C(C(=NC=3C2=CC(CCC#N)=C(C3F)C4=C(C)C(Cl)=CC=C4)C=5C=NC(C)=CN5)C1)[C@H]6[C@@]7(C[C@]6(NC7)[H])[H])N8C(=O)COCC8
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Storage Temperature
-20°C
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Shipping Conditions
Ice Packs
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Category
Small Compound