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Molfinity

INCB3344 - CAS 1262238-11-8

INCB3344 - CAS 1262238-11-8

MF-0093939-01

$57.84 USD
$57.84 USD
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Product Details

  • Bioactivity

    INCB3344 is an effective, specific and orally bioavailable CCR2 antagonist with IC50 values of 9.5 nM (mCCR2) and 5.1 nM (hCCR2) in binding antagonism and 7.8 nM (mCCR2) and in 3.8 nM (hCCR2) antagonism of chemotaxis activity.

  • Target

    CCR

  • Related Pathways

    Immunology/Inflammation, GPCR/G Protein, Microbiology/Virology

  • CAS Number

    1262219

  • Purity

    0.982

  • Molecular Formula

    C29H34F3N3O6

  • Molecular Weight

    577.59

  • SMILES

    [H][C@@]1(CC[C@](O)(CC1)c1ccc2OCOc2c1)N1C[C@H](NC(=O)CNC(=O)c2cccc(c2)C(F)(F)F)[C@H](C1)OCC

  • Storage Temperature

    -20°C

  • Shipping Conditions

    Ice Packs

  • Category

    Small Compound