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Molfinity

INCB38579 - CAS 1246207-65-7

INCB38579 - CAS 1246207-65-7

MF-0045813-01

$887.13 USD
$887.13 USD
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Product Details

  • Bioactivity

    INCB38579 is a selective, orally active, histamine H4 receptor (HH4R) antagonist that crosses the blood-brain barrier and acts on hH4R (IC50: 4.8 nM), mH4R (IC50: 42 nM), and rH4R (IC50: 32 nM) . INCB38579 has anti-inflammatory and antipruritic effects.

  • Target

    Histamine Receptor, Others

  • Related Pathways

    Neuroscience, Others, Immunology/Inflammation, GPCR/G Protein

  • CAS Number

    1246135

  • Molecular Formula

    C25H34N6O

  • Molecular Weight

    434.58

  • SMILES

    CN1CCN(CC1)c1cc(nc(N)n1)-c1ccc2CCN(Cc2c1)C(=O)CC1CCCC1

  • Storage Temperature

    -20°C

  • Shipping Conditions

    Ice Packs

  • Category

    Small Compound