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Indirubin-3'-monoxime - CAS 160807-49-8
Indirubin-3'-monoxime - CAS 160807-49-8
SKU:MF-0016023-01
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$32.42 USD
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$32.42 USD
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Product Details
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Bioactivity
Indirubin-3'-monoxime (Indirubin-3'-oxime) is a potent inhibitor of GSK3β (IC50: 22 nM) and also inhibits CDKs ((IC50s: 100/180/250 nM for Cdk5/p35, Cdk1/cyclin B, Cdk2/cyclin E) .
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Target
GSK-3, Lipoxygenase, CDK
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Related Pathways
Stem Cells, PI3K/Akt/mTOR signaling, Metabolism, Cell Cycle/Checkpoint
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CAS Number
160750
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Purity
0.9965
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Molecular Formula
C16H11N3O2
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Molecular Weight
277.28
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SMILES
ON=C1C(Nc2ccccc12)=C1C(=O)Nc2ccccc12
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Storage Temperature
-20°C
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Shipping Conditions
Ice Packs
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Category
Small Compound