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Molfinity

Indirubin-3'-monoxime - CAS 160807-49-8

Indirubin-3'-monoxime - CAS 160807-49-8

SKU:MF-0016023-01

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  • Bioactivity

    Indirubin-3'-monoxime (Indirubin-3'-oxime) is a potent inhibitor of GSK3β (IC50: 22 nM) and also inhibits CDKs ((IC50s: 100/180/250 nM for Cdk5/p35, Cdk1/cyclin B, Cdk2/cyclin E) .

  • Target

    GSK-3, Lipoxygenase, CDK

  • Related Pathways

    Stem Cells, PI3K/Akt/mTOR signaling, Metabolism, Cell Cycle/Checkpoint

  • CAS Number

    160750

  • Purity

    0.9965

  • Molecular Formula

    C16H11N3O2

  • Molecular Weight

    277.28

  • SMILES

    ON=C1C(Nc2ccccc12)=C1C(=O)Nc2ccccc12

  • Storage Temperature

    -20°C

  • Shipping Conditions

    Ice Packs

  • Category

    Small Compound