Indirubin-5-sulfonate - CAS 244021-67-8

Indirubin-5-sulfonate shows inhibitory activity against GSK-3β. Indirubin-5-sulfonate is a cyclin-dependent kinase (CDK) inhibitor, with IC50 values of 55 nM, 35 nM, 150 nM, 300 nM and 65 nM for CDK1/cyclin B, CDK2/cyclin A, CDK2/cyclin E, CDK4/cyclin D1, and CDK5/p35, respectively.

GSK-3, Others, CDK

Stem Cells, Cell Cycle/Checkpoint, PI3K/Akt/mTOR signaling, Others

243946

C16H10N2O5S

342.33

O=C1C(C=2C(N1)=CC=C(S(=O)(=O)O)C2)=C3C(=O)C=4C(N3)=CC=CC4

-20°C

Ice Packs

Small Compound