Indomethacin sodium hydrate - CAS 74252-25-8

Indomethacin sodium hydrate is an effective orally active, competitive, and reversible inhibitor of COX-1 and COX-2, with IC50 values of 18 nM and 26 nM, respectively. It possesses anti-inflammatory, anticancer, and antimicrobial activities and is commonly used in research related to cancer, inflammation, and viral infections. Additionally, it can induce migraines and gastrointestinal injury and is used to study increased intracranial pressure secondary to severe traumatic brain injury in adults, as well as rheumatoid arthritis. It can also be used to induce gastric ulcer models.

COX

Immunology/Inflammation, Neuroscience

74219

0.9945

C19H21ClNNaO7

433.82

O=C([O-])CC1=C(N(C2=C1C=C(OC)C=C2)C(C3=CC=C(Cl)C=C3)=O)C.[Na+].O.O.O

-20°C

Ice Packs

Small Compound