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Indoximod - CAS 110117-83-4
Indoximod - CAS 110117-83-4
SKU:MF-0005194-01
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$32.42 USD
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$32.42 USD
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Product Details
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Bioactivity
Indoximod (NLG-8189) is a methylated tryptophan with immune checkpoint inhibitory activity. Indoximod inhibits the enzyme indoleamine 2, 3-dioxygenase (IDO), which degrades the essential amino acid tryptophan, and may increase or maintain tryptophan levels important to T cell function. Tryptophan depletion is associated with immunosuppression involving T cell arrest and anergy.
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Target
Indoleamine 2,3-Dioxygenase (IDO), IDO
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Related Pathways
Metabolism
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CAS Number
110030
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Purity
0.9955
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Molecular Formula
C12H14N2O2
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Molecular Weight
218.25
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SMILES
Cn1cc(C[C@@H](N)C(O)=O)c2ccccc12
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Storage Temperature
-20°C
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Shipping Conditions
Ice Packs
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Category
Small Compound