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Molfinity

Indoximod - CAS 110117-83-4

Indoximod - CAS 110117-83-4

SKU:MF-0005194-01

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  • Bioactivity

    Indoximod (NLG-8189) is a methylated tryptophan with immune checkpoint inhibitory activity. Indoximod inhibits the enzyme indoleamine 2, 3-dioxygenase (IDO), which degrades the essential amino acid tryptophan, and may increase or maintain tryptophan levels important to T cell function. Tryptophan depletion is associated with immunosuppression involving T cell arrest and anergy.

  • Target

    Indoleamine 2,3-Dioxygenase (IDO), IDO

  • Related Pathways

    Metabolism

  • CAS Number

    110030

  • Purity

    0.9955

  • Molecular Formula

    C12H14N2O2

  • Molecular Weight

    218.25

  • SMILES

    Cn1cc(C[C@@H](N)C(O)=O)c2ccccc12

  • Storage Temperature

    -20°C

  • Shipping Conditions

    Ice Packs

  • Category

    Small Compound