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Indusatumab vedotin - CAS 1514889-12-3
Indusatumab vedotin - CAS 1514889-12-3
SKU:MF-0100593-01
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Product Details
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Bioactivity
Indusatumab vedotin (MLN-0264; AKT-264) is an antibody-drug conjugate (ADC) that combines a human anti-guanylate cyclase C (GCC) antibody with the microtubule-disruptor monomethyl auristatin E, demonstrating anti-proliferative effects on pancreatic cancer cell lines by arresting the cell cycle at the G2/M phase and inducing apoptosis [1].
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Target
Others, Antibody-Drug Conjugates (ADCs), Apoptosis, Guanylate cyclase
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Related Pathways
GPCR/G Protein, Apoptosis, Antibody-drug Conjugate/ADC Related, Others
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CAS Number
1514889-12-3
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Storage Temperature
-20°C
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Shipping Conditions
Ice Packs
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Category
Inhibitory Antibodies