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Ingenol mebutate - CAS 75567-37-2

Ingenol mebutate - CAS 75567-37-2

SKU:MF-0015316-01

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  • Bioactivity

    Ingenol mebutate (Ingenol 3-Angelate) is a potent activator of PKC subtypes including PKC-α, PKC-β, PKC-γ, PKC-δ, and PKC-ε with Kis of 0.3, 0.105, 0.162, 0.376, and 0.171 nM. Ingenol mebutate exhibits antiinflammatory and antitumor activity.

  • Target

    PKC, HIV Protease, gp120/CD4

  • Related Pathways

    Immunology/Inflammation, Chromatin/Epigenetic, Proteases/Proteasome, Cytoskeletal Signaling, Microbiology/Virology

  • CAS Number

    75528

  • Purity

    0.9976

  • Molecular Formula

    C25H34O6

  • Molecular Weight

    430.53

  • SMILES

    C\C=C(\C)C(=O)O[C@H]1C(C)=C[C@@]23[C@H](C)C[C@@H]4[C@H]([C@H](C=C(CO)[C@@H](O)[C@]12O)C3=O)C4(C)C

  • Storage Temperature

    -20°C

  • Shipping Conditions

    Ice Packs

  • Category

    Natural Product