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Ingenol mebutate - CAS 75567-37-2
Ingenol mebutate - CAS 75567-37-2
SKU:MF-0015316-01
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Product Details
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Bioactivity
Ingenol mebutate (Ingenol 3-Angelate) is a potent activator of PKC subtypes including PKC-α, PKC-β, PKC-γ, PKC-δ, and PKC-ε with Kis of 0.3, 0.105, 0.162, 0.376, and 0.171 nM. Ingenol mebutate exhibits antiinflammatory and antitumor activity.
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Target
PKC, HIV Protease, gp120/CD4
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Related Pathways
Immunology/Inflammation, Chromatin/Epigenetic, Proteases/Proteasome, Cytoskeletal Signaling, Microbiology/Virology
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CAS Number
75528
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Purity
0.9976
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Molecular Formula
C25H34O6
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Molecular Weight
430.53
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SMILES
C\C=C(\C)C(=O)O[C@H]1C(C)=C[C@@]23[C@H](C)C[C@@H]4[C@H]([C@H](C=C(CO)[C@@H](O)[C@]12O)C3=O)C4(C)C
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Storage Temperature
-20°C
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Shipping Conditions
Ice Packs
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Category
Natural Product