Inostamycin A - CAS 129905-10-8

Inostamycin A, a bacterial metabolite isolated from Streptomyces with antimicrobial and anticancer activity, is a selective inhibitor of CDP-diacylglycerol:inositol 3-phosphatidyltransferase, thereby blocking the phosphatidylinositol turnover.Inostamycin A induces apoptosis in cancer cells and exhibits concentration-dependent cytotoxicity in a variety of cancer cell lines.

Endogenous Metabolite

Metabolism

129887

C38H68O11

700.94

O[C@]1(O[C@]([C@H](CCC)O)(CC)C[C@H]1C)[C@@]2(C)O[C@]([C@H](C([C@H]([C@H]([C@H](C)[C@@]3([C@@H](CC)[C@@H](O)[C@H](C)[C@@]([C@H](C(O)=O)CC)(O)O3)[H])O)C)=O)CC)([C@@H](C)C2)[H]

-20°C

Ice Packs

Natural Product