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Molfinity

INT-777 - CAS 1199796-29-6

INT-777 - CAS 1199796-29-6

MF-0016325-01

$137.94 USD
$137.94 USD
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Product Details

  • Bioactivity

    INT-777 (S-EMCA) is a potent TGR5 agonist with an EC50 of 0.82 μM. INT-777 (S-EMCA) inhibits NLRP5-ASC inflammasome-mediated neuroinflammation via the TGR3/cAMP/PKA signaling pathway after subarachnoid hemorrhage in rats.

  • Target

    GPCR19

  • Related Pathways

    GPCR/G Protein

  • CAS Number

    1199761

  • Purity

    0.9989

  • Molecular Formula

    C27H46O5

  • Molecular Weight

    450.65

  • SMILES

    [H][C@@]12CC[C@H]([C@H](C)C[C@H](C)C(O)=O)[C@@]1(C)[C@@H](O)C[C@@]1([H])[C@@]2([H])[C@H](O)[C@H](CC)[C@]2([H])C[C@H](O)CC[C@]12C

  • Storage Temperature

    -20°C

  • Shipping Conditions

    Ice Packs

  • Category

    Small Compound