IQ-1S - CAS 1421610-21-0

IQ-1S is an inhibitor of NF-κB/activating protein 1 (AP-1) with an IC50 of 1.8 μM. It exhibits high binding affinity to all three JNKs, with Kd values for JNK3, JNK2, and JNK1 being 87 nM, 360 nM, and 390 nM, respectively.

JNK

MAPK

1421589

C15H8N3NaO

269.23

[O-]N=C1C2=C(C3=CC=CC=C13)N=C4C=CC=CC4=N2.[Na+]

-20°C

Ice Packs

Small Compound