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Molfinity

IQ-1S free acid - CAS 23146-22-7

IQ-1S free acid - CAS 23146-22-7

SKU:MF-0094122-01

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  • Bioactivity

    IQ-1S free acid (IQ-1S) is an effective and specific c-Jun N-Terminal Kinase Inhibitor. IQ-1S inhibits murine delayed-type hypersensitivity. IQ-1S can reduce inflammation and cartilage loss associated with CIA and can serve as a small-molecule modulator for mechanistic studies of JNK function in rheumatoid arthritis. IQ-1S is highly specific for JNK and that its neutral form is the most abundant species at physiologic pH.

  • Target

    JNK, NF-κB

  • Related Pathways

    MAPK, NF-κB

  • CAS Number

    23117

  • Purity

    0.9905

  • Molecular Formula

    C15H9N3O

  • Molecular Weight

    247.25

  • SMILES

    ON=C1c2ccccc2-c2nc3ccccc3nc12

  • Storage Temperature

    -20°C

  • Shipping Conditions

    Ice Packs

  • Category

    Small Compound