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Molfinity

IQ-3 - CAS 312538-03-7

IQ-3 - CAS 312538-03-7

MF-0093487-01

$35.41 USD
$35.41 USD
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Product Details

  • Bioactivity

    IQ3 is a selective inhibitor of JNK3 (JNK3, JNK1 and JNK2 with Kd of 66 nM, 240 nM and 290 nM, respectively) . IQ 3 inhibits NF-κB/AP1 transcriptional activity in THP1-Blue cells with IC50 of 1.4 μM, also inhibits TNF-α and IL-6 production in vitro.

  • Target

    JNK

  • Related Pathways

    MAPK

  • CAS Number

    312538-03-7

  • Purity

    ≥98%

  • Molecular Formula

    C20H11N3O3

  • Molecular Weight

    341.32

  • SMILES

    O=C(ON=C1c2ccccc2-c2nc3ccccc3nc12)c1ccco1

  • Storage Temperature

    -20°C

  • Shipping Conditions

    Ice Packs

  • Category

    Small Compound