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Ir-CA - CAS 2870682-93-0
Ir-CA - CAS 2870682-93-0
SKU:MF-0120811-01
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Product Details
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Bioactivity
Ir-CA is an antitumor agent that accumulates in mitochondria, inducing mitochondrial dysfunction, apoptosis, and autophagy. It initiates mitophagy and cell cycle arrest to kill Cisplatin-resistant A549R cells and effectively inhibits metastasis by inhibiting MMP-2/MMP-9 [1].
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Target
Apoptosis, Autophagy
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Related Pathways
Apoptosis, Autophagy
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CAS Number
2870682-93-0
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Molecular Formula
C43H35F6IrN5OP
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Molecular Weight
974.95
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SMILES
[P+5]([F-])([F-])([F-])([F-])([F-])[F-].C(NC(/C=C/C1=CC=CC=C1)=O)C=2C=C3[N]([Ir+3]45([N]=6C3=CC(C)=CC6)([C-]=7C(C=8[N]4=CC=CC8)=CC=CC7)[C-]=9C(C=%10[N]5=CC=CC%10)=CC=CC9)=CC2
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Storage Temperature
-20°C
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Shipping Conditions
Ice Packs
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Category
Small Compound