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IRAK4-IN-13 - CAS 2667681-57-2
IRAK4-IN-13 - CAS 2667681-57-2
SKU:MF-0051688-01
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$1,383.80 USD
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$1,383.80 USD
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Product Details
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Bioactivity
IRAK4-IN-13 (compound 21) is a selective and potent IRAK4 inhibitor with an IC50 of 0.6 nM and exhibits high metabolic clearance, possessing an intrinsic human liver microsomal (HLM) clearance of 96 μL/min/mg.
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Target
Others, IRAK
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Related Pathways
Others, NF-κB, Immunology/Inflammation
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CAS Number
2667622
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Molecular Formula
C24H27N9O
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Molecular Weight
457.53
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SMILES
O(C=1C2=C(N=C(NC3=CN(N=C3)C4CCN(C)CC4)N1)C=CC(=N2)C=5C=NC=NC5)C6(C)CC6
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Storage Temperature
-20°C
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Shipping Conditions
Ice Packs
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Category
Small Compound