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IRAK4-IN-15 - CAS 2667681-85-6

IRAK4-IN-15 - CAS 2667681-85-6

MF-0045911-01

$1,383.80 USD
$1,383.80 USD
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Product Details

  • Bioactivity

    IRAK4-IN-15 is a selective and potent IRAK4 inhibitor (IC50: 0.002 μM) with good human PK prediction and low intrinsic clearance.IRAK4-IN-15 in combination with Acalabrutinib exhibited potent synergistic in vitro activity against MyD88/CD79 double mutant ABC-DLBCL.

  • Target

    Others, IRAK

  • Related Pathways

    NF-κB, Others, Immunology/Inflammation

  • CAS Number

    2667590

  • Molecular Formula

    C25H29FN10

  • Molecular Weight

    488.56

  • SMILES

    CN1CC2(CC(C2)N3C=C(NC4=NC5=C(C(NC(C)C)=N4)N=C(C(F)=C5)C=6C=NC(C)=NC6)C=N3)C1

  • Storage Temperature

    -20°C

  • Shipping Conditions

    Ice Packs

  • Category

    Small Compound