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IRAK4-IN-16 - CAS 1812188-83-2

IRAK4-IN-16 - CAS 1812188-83-2

MF-0006408-01

$1,383.80 USD
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Product Details

  • Bioactivity

    IRAK4-IN-16 (compound 4) is a potent inhibitor of interleukin-1 receptor associated kinase 4 (IRAK4) with an IC50 of 2.5 nM. It exhibits cytotoxicity against OCI-LY10, TMD8, Ramos, and HT cells, with IC50 values of 0.2, 0.2, 0.6, and 2.7 μM, respectively [1].

  • Target

    IRAK, Others

  • Related Pathways

    Immunology/Inflammation, Others, NF-κB

  • CAS Number

    1812188-83-2

  • Molecular Formula

    C17H20F2N8O

  • Molecular Weight

    390.39

  • SMILES

    C(NC=1C(C(F)F)=NN(C)C1)(=O)C2=C3N(N=C2)C=CC(N[C@@H]4CCCNC4)=N3

  • Storage Temperature

    -20°C

  • Shipping Conditions

    Ice Packs

  • Category

    Small Compound