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IRAK4-IN-28 - CAS 2952532-92-0
IRAK4-IN-28 - CAS 2952532-92-0
SKU:MF-0147114-01
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$1,778.67 USD
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$1,778.67 USD
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Product Details
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Bioactivity
IRAK4-IN-28 (compound 42), an orally-active IRAK4 inhibitor (IC50=8.9 nM), exhibits strong binding affinity with a Kd of 0.58 nM for the target enzyme. It is utilized for research purposes in the study of inflammation and autoimmune diseases [1].
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Target
IRAK
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Related Pathways
NF-κB, Immunology/Inflammation
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CAS Number
2952440
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Molecular Formula
C27H31N9O3
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Molecular Weight
529.59
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SMILES
C(NC=1N=C(C=CC1)C=2C=NN(C)C2)(=O)C3=C(N=C4C(=C3)OC(=N4)N5CCOCC5)N6CCN(CC6)C7CC7
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Storage Temperature
-20°C
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Shipping Conditions
Ice Packs
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Category
Small Compound