IRF1-IN-1 - CAS 701225-07-2

IRF1-IN-1 (Compound I-2) is an IRF1 inhibitor that reduces IRF1 recruitment to the Caspase 1 promoter, inhibiting the cleavage of Caspase 1, GSDMD, IL-1, and PARP1, thereby protecting against skin inflammatory damage.

Interleukin, PARP, Pyroptosis, Caspase, IL Receptor, IFNAR

Proteases/Proteasome, Immunology/Inflammation, Apoptosis, DNA Damage/DNA Repair, Chromatin/Epigenetic

701225-07-2

0.9988

C22H24N4O4S

440.52

O=C1C=2C=CC=CC2N=CN1CCC(=O)NC3=CC=C(C=C3)S(=O)(=O)N4CCCCC4

-20°C

Ice Packs

Small Compound