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Molfinity

Irinotecan - CAS 97682-44-5

Irinotecan - CAS 97682-44-5

SKU:MF-0013398-01

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  • Bioactivity

    Irinotecan (CPT-11), a derivative of camptothecin, is an inhibitor of DNA topoisomerase I (Topo I) . Irinotecan has antitumor activity by preventing DNA strand reattachment through binding to the Topo I complex, resulting in double-stranded DNA breaks and cell death.

  • Target

    Topoisomerase, Autophagy

  • Related Pathways

    Autophagy, DNA Damage/DNA Repair

  • CAS Number

    97633

  • Purity

    >99.99%

  • Molecular Formula

    C33H38N4O6

  • Molecular Weight

    586.68

  • SMILES

    CCc1c2Cn3c(cc4c(COC(=O)[C@]4(O)CC)c3=O)-c2nc2ccc(OC(=O)N3CCC(CC3)N3CCCCC3)cc12

  • Storage Temperature

    -20°C

  • Shipping Conditions

    Ice Packs

  • Category

    Small Compound