Isocryptotanshinone - CAS 22550-15-8

Isocryptotanshinone inhibits protein tyrosine phosphatase 1B (PTP1B) activity with 50% inhibitory concentration values of 56.1±6.3 μM, PTP1B acts as a negative regulator of insulin signaling, and selective inhibition of PTP1B has served as a potential drug target for the treatment of type 2 diabetes.

STAT, JNK, ERK

JAK/STAT signaling, MAPK, Stem Cells

22527

C19H20O3

296.36

O=C1C=2C3=C(C=CC2C(=O)C4=C1OC[C@H]4C)C(C)(C)CCC3

-20°C

Ice Packs

Natural Product