Isodunnianol - CAS 139726-30-0

Isodunnianol exhibits anti-AChE activity with an IC50 value of 13.0 uM; it also exhibits neurite outgrowth-promoting activity at the concentration ranging from 0.1 to 10 uM in the primary cultured rat cortical neurons. Isodunnianol, dunnianol, and Macranthol have anti-inflammatory activity, they can increase NAG-1 (multiple targets related to inflammation) activity 1.5 -3.0 fold and decrease cellular oxidative stress by 40-65%, they show substantial activity against iNOS.

Autophagy, AChR, NF-κB, NOS, ROS

NF-κB, Immunology/Inflammation, Autophagy, Neuroscience

139726-30-0

C27H26O3

398.502

Oc1ccc(CC=C)cc1-c1cc(CC=C)cc(Oc2ccc(CC=C)cc2)c1O

-20°C

Ice Packs

Natural Product