Isoliquiritin apioside - CAS 120926-46-7

Isoliquiritin apioside, isolated from Glycyrrhizae radix rhizome, significantly decreases PMA-induced increases in MMP9 activities and suppresses PMA-induced activation of MAPK and NF-κB. Isoliquiritin apioside auppresseses invasiveness and angiogenesis of cancer cells and endothelial cells. Isoliquiritin apioside has marked potential to combat oxidative stress-induced genotoxicity.

P38 MAPK, NF-κB, MMP

NF-κB, MAPK, Proteases/Proteasome

120873

0.9927

C26H30O13

550.51

[H][C@]1(O[C@@H]2OC[C@](O)(CO)[C@H]2O)[C@H](Oc2ccc(\C=C\C(=O)c3ccc(O)cc3O)cc2)O[C@H](CO)[C@@H](O)[C@@H]1O

-20°C

Ice Packs

Natural Product