Isorhamnetin-3-O-glucoside - CAS 5041-82-7

Isorhamnetin-3-O-glucoside (Isorhamnetin-3-O-beta-D-Glucoside) inhibits the activity of alpha-glucosidase from rat intestine; it exhibits a potent rat lens aldose reductase (RLAR) inhibition in vitro, its IC (50) being 1.4 microM and has inhibitory effects of sorbitol accumulation, suggests that it is a leading compound for further study as a new drug for the prevention and/or treatment of diabetes and its complications.

Others, PI3K, PERK, Akt, Lipase, ERK

Apoptosis, MAPK, Cytoskeletal Signaling, Others, PI3K/Akt/mTOR signaling, Metabolism

4952

0.9981

C22H22O12

478.4

COc1cc(ccc1O)-c1oc2cc(O)cc(O)c2c(=O)c1O[C@@H]1O[C@H](CO)[C@@H](O)[C@H](O)[C@H]1O

-20°C

Ice Packs

Natural Product