Isotenulin - CAS 10092-04-3

Isotenulin inhibits the efflux function of P-glycoprotein (P-gp) by stimulating P-glycoprotein ATPase, helping to overcome multidrug resistance (MDR) in cancer cells. It exhibits cytotoxicity in multidrug-resistant cancer cells KB-vin and in sensitive cancer cells HeLaS3. Additionally, Isotenulin acts synergistically with Paclitaxel, Vinblastine, and Doxorubicin.

P-gp

Membrane transporter/Ion channel, Neuroscience

10092-04-03

C17H22O5

306.354

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-20°C

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Natural Product