Isotretinoin - CAS 4759-48-2

Isotretinoin (13-cis-Retinoic acid) binds to and activates nuclear retinoic acid receptors (RARs), which act as transcription factors that promote cell differentiation and apoptosis. This naturally occurring retinoic acid has potential antineoplastic activity, exhibits immunomodulatory and anti-inflammatory responses, and inhibits ornithine decarboxylase, thereby decreasing polyamine synthesis and keratinization.

Endogenous Metabolite, Retinoid Receptor, Autophagy

Autophagy, Metabolism

4709

0.9961

C20H28O2

300.44

C(=C/C(=C/C=C/C(=C\C(O)=O)/C)/C)\C=1C(C)(C)CCCC1C

-20°C

Ice Packs

Natural Product