Israpafant - CAS 117279-73-9

Israpafant is a selective antagonist for the platelet-activating factor receptor (IC50 = 0.84nM) . Israpafant inhibits PAF-induced human platelet aggregation. Israpafant inhibits the activation of eosinophil cells and consequently delays the development of immune responses. Israpafant also has anti-nephrotoxic properties and to mobilize calcium transport.

PAFR, Others

GPCR/G Protein, Others

117197

C28H29ClN4S

489.07

CC=1N2C3=C(C(=NC(C)C2=NN1)C4=C(Cl)C=CC=C4)C=C(CCC5=CC=C(CC(C)C)C=C5)S3

-20°C

Ice Packs

Small Compound