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Molfinity

ISRIB (trans-isomer) - CAS 1597403-47-8

ISRIB (trans-isomer) - CAS 1597403-47-8

MF-0092939-01

$33.17 USD
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Product Details

  • Bioactivity

    ISRIB (trans-isomer) is a potent inhibitor of PERK (IC50=5 nM) that restores protein translation and prevents SG formation in the presence of P-eIF2α.

  • Target

    Autophagy, Apoptosis, PERK

  • Related Pathways

    Autophagy, Apoptosis

  • CAS Number

    1597348

  • Purity

    0.9927

  • Molecular Formula

    C22H24Cl2N2O4

  • Molecular Weight

    451.34

  • SMILES

    Clc1ccc(OCC(=O)N[C@H]2CC[C@@H](CC2)NC(=O)COc2ccc(Cl)cc2)cc1

  • Storage Temperature

    -20°C

  • Shipping Conditions

    Ice Packs

  • Category

    Small Compound