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Itacnosertib (hydrocholide) - CAS 2409543-84-4
Itacnosertib (hydrocholide) - CAS 2409543-84-4
SKU:MF-0119993-01
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Product Details
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Bioactivity
Itacnosertib hydrochloride acts as an inhibitor targeting JAK2, ACVR1 (ALK2), and ALK5 [1].
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Target
TGF-beta/Smad, PI3K, ALK, FLT, Akt, Others, mTOR, JAK, STAT
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Related Pathways
JAK/STAT signaling, Others, PI3K/Akt/mTOR signaling, Chromatin/Epigenetic, Tyrosine Kinase/Adaptors, Angiogenesis, Cytoskeletal Signaling, Stem Cells
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CAS Number
2409543-84-4
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Molecular Formula
C26H29ClN8O
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Molecular Weight
505.01
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SMILES
O(C)C1=C(C=CC(NC=2N=C(NC3=C(N=CC=C3)C4=CC=CC=N4)C=CN2)=C1)N5CCN(C)CC5.Cl
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Storage Temperature
-20°C
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Shipping Conditions
Ice Packs
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Category
Small Compound