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Itacnosertib (hydrocholide) - CAS 2409543-84-4

Itacnosertib (hydrocholide) - CAS 2409543-84-4

SKU:MF-0119993-01

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  • Bioactivity

    Itacnosertib hydrochloride acts as an inhibitor targeting JAK2, ACVR1 (ALK2), and ALK5 [1].

  • Target

    TGF-beta/Smad, PI3K, ALK, FLT, Akt, Others, mTOR, JAK, STAT

  • Related Pathways

    JAK/STAT signaling, Others, PI3K/Akt/mTOR signaling, Chromatin/Epigenetic, Tyrosine Kinase/Adaptors, Angiogenesis, Cytoskeletal Signaling, Stem Cells

  • CAS Number

    2409543-84-4

  • Molecular Formula

    C26H29ClN8O

  • Molecular Weight

    505.01

  • SMILES

    O(C)C1=C(C=CC(NC=2N=C(NC3=C(N=CC=C3)C4=CC=CC=N4)C=CN2)=C1)N5CCN(C)CC5.Cl

  • Storage Temperature

    -20°C

  • Shipping Conditions

    Ice Packs

  • Category

    Small Compound