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Molfinity

ITX3 - CAS 347323-96-0

ITX3 - CAS 347323-96-0

SKU:MF-0033072-01

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  • Bioactivity

    ITX3 is a specific, non-toxic, active and selective TrioN RhoGEF inhibitor with IC50 of 76 μM. ITX3 has anticancer effects, inhibits trion mediated GTP exchange on RhoG and Rac1, inhibits NGF-mediated neurite growth in PC12 cells and REF52 fibroblast structure formation induced by trion.

  • Target

    ROCK, Rho, Others

  • Related Pathways

    Cytoskeletal Signaling, Cell Cycle/Checkpoint, Stem Cells, Others

  • CAS Number

    347227

  • Purity

    0.9902

  • Molecular Formula

    C22H17N3OS

  • Molecular Weight

    371.45

  • SMILES

    Cc1cc(\C=c2\sc3nc4ccccc4n3c2=O)c(C)n1-c1ccccc1

  • Storage Temperature

    -20°C

  • Shipping Conditions

    Ice Packs

  • Category

    Small Compound