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Molfinity

IWP-3 - CAS 687561-60-0

IWP-3 - CAS 687561-60-0

MF-0018155-01

$39.15 USD
$39.15 USD
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Product Details

  • Bioactivity

    IWP-3 is a potent inhibitor of Wnt production with an IC50 of 40 nM. It inhibits Porcupine (Porcn), blocking the palmitoylation of Wnt proteins, and moderately inhibits CK1γ3 and CK1ε, but does not inhibit CK1α [1] [2].

  • Target

    Wnt/beta-catenin

  • Related Pathways

    Cytoskeletal Signaling, Stem Cells

  • CAS Number

    687501

  • Purity

    0.9838

  • Molecular Formula

    C22H17FN4O2S3

  • Molecular Weight

    484.59

  • SMILES

    Cc1ccc2nc(NC(=O)CSc3nc4CCSc4c(=O)n3-c3ccc(F)cc3)sc2c1

  • Storage Temperature

    -20°C

  • Shipping Conditions

    Ice Packs

  • Category

    Small Compound