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Molfinity

Ixazomib - CAS 1072833-77-2

Ixazomib - CAS 1072833-77-2

MF-0015567-01

$40.65 USD
$40.65 USD
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Product Details

  • Bioactivity

    Ixazomib (MLN2238), a second generation, boron-containing peptide proteasome inhibitor (PI), inhibits the chymotrypsin-like proteolytic (β5) site of the 20S proteasome (IC50/Ki: 3.4/0.93 nM, in cell-free assays), also inhibits the caspase-like (β1) and trypsin-like (β2) proteolytic sites (IC50: 31/3500 nM) .

  • Target

    Proteasome, Caspase, Autophagy

  • Related Pathways

    Proteases/Proteasome, Apoptosis, Autophagy, Ubiquitination

  • CAS Number

    1072754

  • Purity

    0.9977

  • Molecular Formula

    C14H19BCl2N2O4

  • Molecular Weight

    361.03

  • SMILES

    CC(C)C[C@H](NC(=O)CNC(=O)c1cc(Cl)ccc1Cl)B(O)O

  • Storage Temperature

    -20°C

  • Shipping Conditions

    Ice Packs

  • Category

    Small Compound