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Molfinity

Izuforant - CAS 1429374-83-3

Izuforant - CAS 1429374-83-3

MF-0140569-01

$1,383.80 USD
$1,383.80 USD
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Product Details

  • Bioactivity

    Izuforant (JW1601) (Compound 24) exhibits potent anti-inflammatory and anti-pruritic activities, with a binding affinity for human serotonin 3 receptor (h5-HT3R) and an IC50 value of 9.1 μM. It is also an orally active antagonist of histamine H4 receptor (H4R), showing an IC50 value of 36 nM against human H4R [1] [2].

  • Target

    Others, Histamine Receptor

  • Related Pathways

    GPCR/G Protein, Others, Neuroscience, Immunology/Inflammation

  • CAS Number

    1429288

  • Molecular Formula

    C12H12BrN7

  • Molecular Weight

    334.17

  • SMILES

    N(C)C1CN(C=2C=3N(C=4C(N2)=NC=C(Br)C4)C=NN3)C1

  • Storage Temperature

    -20°C

  • Shipping Conditions

    Ice Packs

  • Category

    Small Compound