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J-1063 - CAS 2374772-46-8
J-1063 - CAS 2374772-46-8
SKU:MF-0046147-01
Regular price
$1,383.80 USD
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$1,383.80 USD
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Product Details
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Bioactivity
J-1063 is a selective, orally active and potent inhibitor of ALK5 (IC50: 0.039 μM) . J-1063 inhibits inflammatory infiltration, collagen deposition, hepatocyte necrosis and exhibits anti-fibrotic effects. j-1063 has potential for liver fibrosis studies.
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Target
Others, TGF-beta/Smad
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Related Pathways
Others, Stem Cells
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CAS Number
2374718
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Molecular Formula
C24H19N5OS
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Molecular Weight
425.51
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SMILES
C(C(NC1=CC=CC=C1)=O)N2C=C(C(=N2)C=3N=C(C)C=CC3)C4=CC=5C(S4)=CC=NC5
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Storage Temperature
-20°C
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Shipping Conditions
Ice Packs
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Category
Small Compound