(±) -J 113397 - CAS 217461-40-0

(±) -J-113397 is a potent and selective non-peptidyl ORL1 receptor antagonist (K (i) : cloned human ORL1=1.8 nM) . J-113397 inhibited nociceptin/orphanin FQ-stimulated GTPγS binding to CHO cells expressing ORL1 with an IC50 value of 5.3 nM. J-113397 can be used for researching the physiological roles of nociceptin/orphanin FQ [1].

Others, Opioid Receptor

GPCR/G Protein, Endocrinology/Hormones, Neuroscience, Others

217421

C24H37N3O2

399.57

O=C1N(C=2C(N1CC)=CC=CC2)[C@@H]3[C@@H](CO)CN(CC4CCCCCCC4)CC3

-20°C

Ice Packs

Small Compound