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JAK 3 inhibitor IV - CAS 58753-54-1
JAK 3 inhibitor IV - CAS 58753-54-1
SKU:MF-0020825-01
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Product Details
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Bioactivity
JAK 3 inhibitor IV (ZM 39923 hydrochloride) is a JAK1/3 inhibitor with pIC50 of 4.4/7.1, almost no activity to JAK2 and modestly potent to EGFR; also found to be sensitive to transglutaminase.
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Target
JAK, Glutaminase, EGFR
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Related Pathways
JAK/STAT signaling, Stem Cells, Tyrosine Kinase/Adaptors, Angiogenesis, Chromatin/Epigenetic, Proteases/Proteasome
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CAS Number
58753-54-1
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Purity
0.98
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Molecular Formula
C16H19NO
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Molecular Weight
241.33
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SMILES
O=C(C1=CC=C2C=CC=CC2=C1)CCNC(C)C
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Storage Temperature
-20°C
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Shipping Conditions
Ice Packs
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Category
Small Compound