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Molfinity

JAK-IN-14 - CAS 1973485-06-1

JAK-IN-14 - CAS 1973485-06-1

MF-0094222-01

$88.38 USD
$88.38 USD
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Product Details

  • Bioactivity

    JAK-IN-14 (compound 16) is a specific JAK1 inhibitor with IC50<5 μM. It prevents JAK1 phosphorylation by binding to the active site of JAK1, and is more than 8-fold selective for JAK1 over JAK2/JAK3, and can be used in immune, inflammation and cancer research.

  • Target

    JAK

  • Related Pathways

    Angiogenesis, Stem Cells, Tyrosine Kinase/Adaptors, Chromatin/Epigenetic, JAK/STAT signaling

  • CAS Number

    1973485-06-1

  • Purity

    0.9827

  • Molecular Formula

    C19H15FN4O

  • Molecular Weight

    334.35

  • SMILES

    N#CCC=1C=CC(=C(F)C1)C2=CC=CC3=NC(=CN32)NC(=O)C4CC4

  • Storage Temperature

    -20°C

  • Shipping Conditions

    Ice Packs

  • Category

    Small Compound