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Molfinity

JAK-IN-20 - CAS 1654776-91-6

JAK-IN-20 - CAS 1654776-91-6

MF-0043784-01

$1,383.80 USD
$1,383.80 USD
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Product Details

  • Bioactivity

    JAK-IN-20 is a potent, orally active, broad-based JAK inhibitor, effective on JAK1 (IC50: 7 nM), JAK2 (IC50: 5 nM), and JAK3 (IC50: 14 nM), exhibiting excellent pharmacokinetic and anti-inflammatory activity in vivo.

  • Target

    Others, JAK

  • Related Pathways

    Angiogenesis, Tyrosine Kinase/Adaptors, Chromatin/Epigenetic, JAK/STAT signaling, Others, Stem Cells

  • CAS Number

    1654679

  • Molecular Formula

    C28H30FN7O2

  • Molecular Weight

    515.58

  • SMILES

    FC=1C(=NC(NC2=CC=C(C=C2)N3CCC(CC3)N4CCOCC4)=NC1)C5=CC=C(C(NCC#N)=O)C=C5

  • Storage Temperature

    -20°C

  • Shipping Conditions

    Ice Packs

  • Category

    Small Compound